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Target
Serine/threonine-protein kinase 33
Ligand
BDBM60511
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
2114±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM60511
Synonyms:
(5E)-2-(benzylamino)-5-(4-hydroxybenzylidene)-2-thiazolin-4-one | (5E)-2-(benzylamino)-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazol-4-one | (5E)-5-[(4-hydroxyphenyl)methylidene]-2-[(phenylmethyl)amino]-1,3-thiazol-4-one | (5E)-5-[(4-hydroxyphenyl)methylidene]-2-[(phenylmethyl)amino]-4-thiazolone | 2-Benzylamino-5-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-thiazol-4-one | MLS000589843 | SMR000217101 | cid_1918543
Type:
Small organic molecule
Emp. Form.:
C17H14N2O2S
Mol. Mass.:
310.37
SMILES:
Oc1ccc(C=C2SC(NCc3ccccc3)=NC2=O)cc1 |w:5.4,c:17|
Structure:
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