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Target
Serine/threonine-protein kinase 33
Ligand
BDBM50421
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
8730±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM50421
Synonyms:
(5E)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-quinone | (5E)-5-[(2,4-dihydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | (5E)-5-[(2,4-dihydroxyphenyl)methylidene]thiazolidine-2,4-dione | (5E)-5-[[2,4-bis(oxidanyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione | MLS000703699 | SMR000274064 | cid_5750547
Type:
Small organic molecule
Emp. Form.:
C10H7NO4S
Mol. Mass.:
237.232
SMILES:
Oc1ccc(\C=C2\SC(=O)NC2=O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: