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Target
Serine/threonine-protein kinase 33
Ligand
BDBM67651
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
<100±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM67651
Synonyms:
3-(6-Amino-5-nitro-4-phenyl-pyridin-2-yl)-4-nitro-phenol | 3-(6-amino-5-nitro-4-phenyl-2-pyridinyl)-4-nitrophenol | 3-(6-amino-5-nitro-4-phenyl-2-pyridyl)-4-nitro-phenol | 3-(6-amino-5-nitro-4-phenylpyridin-2-yl)-4-nitrophenol | 3-(6-azanyl-5-nitro-4-phenyl-pyridin-2-yl)-4-nitro-phenol | MLS001210202 | SMR000504332 | cid_6489264
Type:
Small organic molecule
Emp. Form.:
C17H12N4O5
Mol. Mass.:
352.301
SMILES:
Nc1nc(cc(-c2ccccc2)c1[N+]([O-])=O)-c1cc(O)ccc1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: