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TargetGuanine nucleotide-binding protein G(o), alpha subunit 1
LigandBDBM67700
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds
EC50>30000±0 nM
Citation PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Guanine nucleotide-binding protein G(o), alpha subunit 1
Name:Guanine nucleotide-binding protein G(o), alpha subunit 1
Synonyms:guanine nucleotide-binding protein G(o) subunit alpha isoform a
Type:PROTEIN
Mol. Mass.:40043.59
Organism:Homo sapiens (Human)
Description:ChEMBL_321106
Residue:354
Sequence:
MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM67700
NameBDBM67700
Synonyms:3-chloranyl-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-6-nitro-benzothiophene-2-carboxamide | KSC-1-100 | KUC103873N | cid_874677
TypeSmall organic molecule
Emp. Form.C9H5ClN2O3S
Mol. Mass.256.666
SMILESNC(=O)c1sc2cc(ccc2c1Cl)[N+]([O-])=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a