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TargetGuanine nucleotide-binding protein G(o), alpha subunit 1
LigandBDBM67702
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds
EC50>30000±0 nM
Citation PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Guanine nucleotide-binding protein G(o), alpha subunit 1
Name:Guanine nucleotide-binding protein G(o), alpha subunit 1
Synonyms:guanine nucleotide-binding protein G(o) subunit alpha isoform a
Type:PROTEIN
Mol. Mass.:40043.59
Organism:Homo sapiens (Human)
Description:ChEMBL_321106
Residue:354
Sequence:
MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
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  Blast E-value cutoff:
BDBM67702
NameBDBM67702
Synonyms:3-chloranyl-N-(3-imidazol-1-ylpropyl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-imidazol-1-ylpropyl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-N-(3-imidazol-1-ylpropyl)-6-nitro-benzothiophene-2-carboxamide | 3-chloro-N-[3-(1-imidazolyl)propyl]-6-nitro-1-benzothiophene-2-carboxamide | KSC-1-102c | KUC103875N | cid_2933863
TypeSmall organic molecule
Emp. Form.C15H13ClN4O3S
Mol. Mass.364.807
SMILES[O-][N+](=O)c1ccc2c(Cl)c(sc2c1)C(=O)NCCCn1ccnc1
Structure
n/a