Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM68228
Substrate
n/a
Meas. Tech.
High-throughput FP Assay
IC50
4.1e+4±n/a nM
Kd
6.0e+3±n/a nM
Citation
 Carlson, EE; May, JF; Kiessling, LL Chemical probes of UDP-galactopyranose mutase. Chem Biol 13:825-37 (2006) [PubMed]  Article 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM68228
Synonyms:
Thiazolidinone core, 22
Type:
Small organic molecule
Emp. Form.:
C19H14INO3S2
Mol. Mass.:
495.354
SMILES:
OC(=O)C(Cc1ccccc1)N1C(=S)S\C(=C/c2cccc(I)c2)C1=O
Structure:
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