Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM61041
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM61041
Synonyms:
4-phenyl-N-[[4-(propan-2-ylsulfamoyl)anilino]-sulfanylidenemethyl]benzamide | 4-phenyl-N-[[4-(propan-2-ylsulfamoyl)phenyl]carbamothioyl]benzamide | MLS000582313 | N-[({4-[(isopropylamino)sulfonyl]phenyl}amino)carbonothioyl]-4-biphenylcarboxamide | N-[[4-(isopropylsulfamoyl)phenyl]thiocarbamoyl]-4-phenyl-benzamide | SMR000200853 | cid_1252842
Type:
Small organic molecule
Emp. Form.:
C23H23N3O3S2
Mol. Mass.:
453.577
SMILES:
CC(C)NS(=O)(=O)c1ccc(NC(=S)NC(=O)c2ccc(cc2)-c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: