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Target
G-protein coupled receptor 35
Ligand
BDBM68307
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68307
Synonyms:
MLS-0435533.0001 | N,N-diethyl-3-(4-phenylpiperazin-1-yl)carbonyl-4-piperidin-1-yl-benzenesulfonamide | N,N-diethyl-3-(4-phenylpiperazine-1-carbonyl)-4-piperidin-1-ylbenzenesulfonamide | N,N-diethyl-3-(4-phenylpiperazine-1-carbonyl)-4-piperidino-benzenesulfonamide | N,N-diethyl-3-[oxo-(4-phenyl-1-piperazinyl)methyl]-4-(1-piperidinyl)benzenesulfonamide | cid_25702685
Type:
Small organic molecule
Emp. Form.:
C26H36N4O3S
Mol. Mass.:
484.654
SMILES:
CCN(CC)S(=O)(=O)c1ccc(N2CCCCC2)c(c1)C(=O)N1CCN(CC1)c1ccccc1
Structure:
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