Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67427
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
>75418±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67427
Synonyms:
MLS000374660 | N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide | N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-pyrrolidin-1-yl-benzenesulfonamide | N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-pyrrolidin-1-ylbenzenesulfonamide | N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-pyrrolidino-benzenesulfonamide | SMR000244275 | cid_3396597
Type:
Small organic molecule
Emp. Form.:
C20H26FN3O4S2
Mol. Mass.:
455.567
SMILES:
CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(NS(=O)(=O)c2ccc(F)cc2)c1
Structure:
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