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Target
Protein RecA
Ligand
BDBM70364
Substrate
n/a
Meas. Tech.
Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity
EC50
1060±n/a nM
Citation
 PubChem, PC Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM70364
Synonyms:
6-amino-4-(3-furanyl)-3-propyl-2,4-dihydroisoxazolo[5,4-b]pyridine-5-carbonitrile | 6-amino-4-(3-furyl)-3-propyl-2,4-dihydroisoxazolo[5,4-b]pyridine-5-carbonitrile | 6-amino-4-(3-furyl)-3-propyl-4,7-dihydroisoxazolo[5,4-b]pyridine-5-carbonitrile | 6-amino-4-(furan-3-yl)-3-propyl-2,4-dihydro-[1,2]oxazolo[5,4-b]pyridine-5-carbonitrile | 6-azanyl-4-(furan-3-yl)-3-propyl-2,4-dihydro-[1,2]oxazolo[5,4-b]pyridine-5-carbonitrile | MLS000090285 | SMR000024895 | cid_5771370
Type:
Small organic molecule
Emp. Form.:
C14H14N4O2
Mol. Mass.:
270.2866
SMILES:
CCCc1noc2N=C(N)C(C#N)C(c3ccoc3)c12 |t:7|
Structure:
Search PDB for entries with ligand similarity: