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TargetG protein-activated inward rectifier potassium channel 1
LigandBDBM34572
Substrate/Competitorn/a
Meas. Tech.Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing
EC50 0.03717±n/a nM
Citation PubChem, PC Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
G protein-activated inward rectifier potassium channel 1
Name:G protein-activated inward rectifier potassium channel 1
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:56581.73
Organism:Rattus norvegicus
Description:gi_13928834
Residue:501
Sequence:
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNL
GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY
TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM
FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE
GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEVVVILE
GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE
QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDISTKLPSKLQKITGREDFPKKLLRMS
STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG
PTRMEGNLPAKLRKMNSDRFT
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BDBM34572
NameBDBM34572
Synonyms:BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058355 | UK 14,304 | cid_2435
TypeSmall organic molecule
Emp. Form.C11H10BrN5
Mol. Mass.292.135
SMILESBrc1c(NC2=NCCN2)ccc2nccnc12 |t:4|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a