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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74487
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74487
Synonyms:
2-[2-(4-chloro-2,3-dimethyl-phenoxy)ethoxy]ethyl-sec-butyl-amine;oxalic acid | MLS000680621 | N-[2-[2-(4-chloranyl-2,3-dimethyl-phenoxy)ethoxy]ethyl]butan-2-amine;ethanedioic acid | N-[2-[2-(4-chloro-2,3-dimethylphenoxy)ethoxy]ethyl]-2-butanamine;oxalic acid | N-[2-[2-(4-chloro-2,3-dimethylphenoxy)ethoxy]ethyl]butan-2-amine;oxalic acid | N-{2-[2-(4-chloro-2,3-dimethylphenoxy)ethoxy]ethyl}-2-butanamine oxalate | SMR000272588 | cid_2935038
Type:
Small organic molecule
Emp. Form.:
C16H26ClNO2
Mol. Mass.:
299.836
SMILES:
CCC(C)NCCOCCOc1ccc(Cl)c(C)c1C
Structure:
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