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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74507
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74507
Synonyms:
MLS000699713 | N-(4,6-dimethyl-2-pyridinyl)-2-(5-methyl-2-thienyl)-4-quinolinecarboxamide | N-(4,6-dimethyl-2-pyridinyl)-2-(5-methyl-2-thiophenyl)-4-quinolinecarboxamide | N-(4,6-dimethyl-2-pyridyl)-2-(5-methyl-2-thienyl)cinchoninamide | N-(4,6-dimethylpyridin-2-yl)-2-(5-methylthiophen-2-yl)quinoline-4-carboxamide | SMR000227204 | cid_1220150
Type:
Small organic molecule
Emp. Form.:
C22H19N3OS
Mol. Mass.:
373.471
SMILES:
Cc1ccc(s1)-c1cc(C(=O)Nc2cc(C)cc(C)n2)c2ccccc2n1
Structure:
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