Reaction Details Report a problem with these data
Target
Aryl hydrocarbon receptor
Ligand
BDBM75518
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR)
EC50
>91680±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) PubChem Bioassay (2010)[AID] 
Target
Name:
Aryl hydrocarbon receptor
Synonyms:
AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor
Type:
PROTEIN
Mol. Mass.:
96143.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1503828
Residue:
848
Sequence:
MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPFPAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAPFENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLYSIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQQQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFVPFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYPMGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQHTHVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFPDLTSSGFL
  
Inhibitor
Name:
BDBM75518
Synonyms:
(4E)-4-[[(8-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazo]methylidene]-3-hydroxy-1-cyclohexa-2,5-dienone | (4E)-4-[[2-(8-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazinyl]methylidene]-3-hydroxycyclohexa-2,5-dien-1-one | (4E)-4-[[2-(8-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazinyl]methylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one | (4E)-4-[[N'-(8-ethyl-5H-[1,2,4]triazin[5,6-b]indol-3-yl)hydrazino]methylene]-3-hydroxy-cyclohexa-2,5-dien-1-one | 2,4-dihydroxybenzaldehyde (8-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone | MLS001163477 | SMR000496754 | cid_5725981
Type:
Small organic molecule
Emp. Form.:
C18H16N6O2
Mol. Mass.:
348.3586
SMILES:
CCc1ccc2[nH]c3nc(N=NCc4ccc(O)cc4O)nnc3c2c1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: