Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM75541
Substrate
n/a
Meas. Tech.
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the vasopressin 1 receptor (V1R)
EC50
>29910±n/a nM
Citation
 PubChem, PC Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the vasopressin 1 receptor (V1R) PubChem Bioassay (2010)[AID] 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM75541
Synonyms:
2-[[5-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-1,3,4-oxadiazol-2-yl]thio]-N-[2-(trifluoromethyl)phenyl]acetamide | 2-[[5-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]ethanamide | 2-[[5-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-1,3,4-oxadiazol-2-yl]thio]-N-[2-(trifluoromethyl)phenyl]acetamide | 2-[[5-(2,5-dimethyl-1-phenylpyrrol-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide | MLS000569286 | SMR000154872 | cid_2368087
Type:
Small organic molecule
Emp. Form.:
C23H19F3N4O2S
Mol. Mass.:
472.483
SMILES:
Cc1cc(c(C)n1-c1ccccc1)-c1nnc(SCC(=O)Nc2ccccc2C(F)(F)F)o1
Structure:
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