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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM75908
Substrate
n/a
Meas. Tech.
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)
IC50
16100±n/a nM
Citation
 PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM75908
Synonyms:
(4E)-5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)-4-pyridazinecarboxaldehyde oxime | (4E)-6-keto-5-(4-methoxyphenoxy)-1-p-cumenyl-pyridazine-4-carbaldehyde oxime | 5-[(E)-hydroxyiminomethyl]-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-one | SR-02000000430 | SR-02000000430-1 | cid_46835790
Type:
Small organic molecule
Emp. Form.:
C21H21N3O4
Mol. Mass.:
379.4091
SMILES:
COc1ccc(Oc2c(CN=O)cnn(-c3ccc(cc3)C(C)C)c2=O)cc1
Structure:
Search PDB for entries with ligand similarity: