Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM75930
Substrate
n/a
Meas. Tech.
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)
IC50
9000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM75930
Synonyms:
SR-02000000466 | SR-02000000466-1 | [1-(4-methylbenzyl)-2-piperidyl]-[4-(4-nitrophenyl)piperazino]methanone | [1-[(4-methylphenyl)methyl]-2-piperidinyl]-[4-(4-nitrophenyl)-1-piperazinyl]methanone | [1-[(4-methylphenyl)methyl]piperidin-2-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone | cid_46846320
Type:
Small organic molecule
Emp. Form.:
C24H30N4O3
Mol. Mass.:
422.52
SMILES:
Cc1ccc(CN2CCCCC2C(=O)N2CCN(CC2)c2ccc(cc2)[N+]([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: