Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM76043
Substrate
n/a
Meas. Tech.
SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 3
EC50
2520±n/a nM
Citation
 PubChem, PC SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM76043
Synonyms:
1-cyclopentyl-2-imino-5-keto-N-methyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 1-cyclopentyl-2-imino-N-methyl-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | 1-cyclopentyl-2-imino-N-methyl-5-oxodipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-azanylidene-1-cyclopentyl-N-methyl-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS-0437141.0001 | cid_706463
Type:
Small organic molecule
Emp. Form.:
C18H19N5O2
Mol. Mass.:
337.3758
SMILES:
CNC(=O)c1cc2c(nc3ccccn3c2=O)n(C2CCCC2)c1=N
Structure:
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