Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM51557
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM51557
Synonyms:
2-azanylidene-N,1-dicyclopentyl-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS000085137 | N,1-dicyclopentyl-2-imino-5-keto-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | N,1-dicyclopentyl-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide | N,1-dicyclopentyl-2-imino-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | N,1-dicyclopentyl-2-imino-5-oxodipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | SMR000019677 | cid_3151386
Type:
Small organic molecule
Emp. Form.:
C22H25N5O2
Mol. Mass.:
391.4662
SMILES:
N=c1c(cc2c(nc3ccccn3c2=O)n1C1CCCC1)C(=O)NC1CCCC1
Structure:
Search PDB for entries with ligand similarity: