Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM76087
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM76087
Synonyms:
2-(2-chlorophenyl)-N-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]quinoline-4-carboxamide | 2-(2-chlorophenyl)-N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-4-quinolinecarboxamide | 2-(2-chlorophenyl)-N-[4-[(3,4-dimethylisoxazol-5-yl)sulfamoyl]phenyl]cinchoninamide | MLS-0257792.0001 | cid_2332853
Type:
Small organic molecule
Emp. Form.:
C27H21ClN4O4S
Mol. Mass.:
532.998
SMILES:
Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3cc(nc4ccccc34)-c3ccccc3Cl)cc2)c1C
Structure:
Search PDB for entries with ligand similarity: