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Target
G-protein coupled receptor 35
Ligand
BDBM76052
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM76052
Synonyms:
MLS-0226851.0001 | N-[4-(diethylsulfamoyl)phenyl]-2-(2-thienyl)cinchoninamide | N-[4-(diethylsulfamoyl)phenyl]-2-thiophen-2-yl-4-quinolinecarboxamide | N-[4-(diethylsulfamoyl)phenyl]-2-thiophen-2-yl-quinoline-4-carboxamide | N-[4-(diethylsulfamoyl)phenyl]-2-thiophen-2-ylquinoline-4-carboxamide | cid_4803470
Type:
Small organic molecule
Emp. Form.:
C24H23N3O3S2
Mol. Mass.:
465.588
SMILES:
CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)-c2cccs2)cc1
Structure:
Search PDB for entries with ligand similarity: