Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM270305
Substrate
n/a
Meas. Tech.
GRP40 FLIPR Assays
pH
7.4±n/a
Temperature
298.15±n/a K
EC50
1.50±n/a nM
Comments
extracted
Citation
 Chobanian, H; DeMong, D; Guo, Y; Hu, Z; Miller, M; Pio, B; Plummer, CW; Xiao, D; Yang, C Antidiabetic compounds US Patent  US10059667 Publication Date 8/28/2018 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM270305
Synonyms:
US10059667, Example 26
Type:
Small organic molecule
Emp. Form.:
C27H29F6NO3
Mol. Mass.:
529.5145
SMILES:
C[C@@H]([C@@H](C1CC1)c1cccc(OC[C@@H]2CCN(Cc3cc(ccc3C(F)(F)F)C(F)(F)F)C2)c1)C(O)=O |r|
Structure:
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