Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM75577
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM75577
Synonyms:
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[1-(phenylmethyl)-4-piperidinyl]benzamide | 4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[1-(phenylmethyl)piperidin-4-yl]benzamide | KSC-11-145-1 | KUC105598N | N-(1-benzyl-4-piperidyl)-4-[(tosylamino)methyl]benzamide | N-(1-benzylpiperidin-4-yl)-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | cid_45479171
Type:
Small organic molecule
Emp. Form.:
C27H31N3O3S
Mol. Mass.:
477.618
SMILES:
Cc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1
Structure:
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