Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM75404
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay - Set 3
IC50
15000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM75404
Synonyms:
1-[2-furanylmethyl-[oxo(2-pyridinyl)methyl]amino]-1-cyclohexanecarboxylic acid propan-2-yl ester | 1-[2-furfuryl(picolinoyl)amino]cyclohexanecarboxylic acid isopropyl ester | KSC-12-15B | KUC104506N | cid_44665689 | propan-2-yl 1-[furan-2-ylmethyl(pyridin-2-ylcarbonyl)amino]cyclohexane-1-carboxylate | propan-2-yl 1-[furan-2-ylmethyl(pyridine-2-carbonyl)amino]cyclohexane-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C21H26N2O4
Mol. Mass.:
370.4421
SMILES:
CC(C)OC(=O)C1(CCCCC1)N(Cc1ccco1)C(=O)c1ccccn1
Structure:
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