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Target
Intestinal-type alkaline phosphatase 1
Ligand
BDBM75679
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase
EC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase PubChem Bioassay (2010)[AID] 
Target
Name:
Intestinal-type alkaline phosphatase 1
Synonyms:
Alpi | PPBI1_RAT
Type:
Enzyme Catalytic Domain
Mol. Mass.:
58396.39
Organism:
Rattus norvegicus (Rat)
Description:
P15693
Residue:
540
Sequence:
MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
  
Inhibitor
Name:
BDBM75679
Synonyms:
4-chloranyl-3-[[(2-hydroxyphenyl)carbonylamino]carbamoyl]-N-(2-methoxyphenyl)-N-methyl-benzenesulfonamide | 4-chloro-3-[[(2-hydroxybenzoyl)amino]carbamoyl]-N-(2-methoxyphenyl)-N-methylbenzenesulfonamide | 4-chloro-3-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-oxomethyl]-N-(2-methoxyphenyl)-N-methylbenzenesulfonamide | 4-chloro-N-(2-methoxyphenyl)-N-methyl-3-[(salicyloylamino)carbamoyl]benzenesulfonamide | MLS001139919 | SMR000709693 | cid_24818116
Type:
Small organic molecule
Emp. Form.:
C22H20ClN3O6S
Mol. Mass.:
489.929
SMILES:
COc1ccccc1N(C)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)NNC(=O)c1ccccc1O
Structure:
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