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Target
Intestinal-type alkaline phosphatase
Ligand
BDBM76168
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase PubChem Bioassay (2010)[AID] 
Target
Name:
Intestinal-type alkaline phosphatase
Synonyms:
ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN
Type:
PROTEIN
Mol. Mass.:
56804.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1278525
Residue:
528
Sequence:
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
  
Inhibitor
Name:
BDBM76168
Synonyms:
4-[2-(3-Methyl-pyridin-2-ylamino)-thiazol-4-yl]-benzene-1,2-diol | 4-[2-[(3-methyl-2-pyridinyl)amino]-4-thiazolyl]benzene-1,2-diol | 4-[2-[(3-methyl-2-pyridyl)amino]thiazol-4-yl]pyrocatechol | 4-[2-[(3-methylpyridin-2-yl)amino]-1,3-thiazol-4-yl]benzene-1,2-diol | MLS000123807 | SMR000124379 | cid_751869
Type:
Small organic molecule
Emp. Form.:
C15H13N3O2S
Mol. Mass.:
299.348
SMILES:
Cc1cccnc1Nc1nc(cs1)-c1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: