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Target
Intestinal-type alkaline phosphatase
Ligand
BDBM76180
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase PubChem Bioassay (2010)[AID] 
Target
Name:
Intestinal-type alkaline phosphatase
Synonyms:
ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN
Type:
PROTEIN
Mol. Mass.:
56804.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1278525
Residue:
528
Sequence:
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
  
Inhibitor
Name:
BDBM76180
Synonyms:
3-Chloro-benzo[b]thiophene-2-carboxylic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide | 3-chloranyl-N-[(5-nitrofuran-2-yl)methylideneamino]-1-benzothiophene-2-carboxamide | 3-chloro-N-[(5-nitro-2-furanyl)methylideneamino]-1-benzothiophene-2-carboxamide | 3-chloro-N-[(5-nitro-2-furyl)methyleneamino]benzothiophene-2-carboxamide | 3-chloro-N-[(5-nitrofuran-2-yl)methylideneamino]-1-benzothiophene-2-carboxamide | MLS000587940 | SMR000212019 | cid_968654
Type:
Small organic molecule
Emp. Form.:
C14H8ClN3O4S
Mol. Mass.:
349.749
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)c2sc3ccccc3c2Cl)o1
Structure:
Search PDB for entries with ligand similarity: