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Target
Sentrin-specific protease 8
Ligand
BDBM76367
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2670±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76367
Synonyms:
MLS000065767 | N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-methyl-3-furamide | N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-methyl-3-furancarboxamide | N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-methyl-furan-3-carboxamide | N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-methylfuran-3-carboxamide | SMR000080448 | cid_1245882
Type:
Small organic molecule
Emp. Form.:
C14H17N3O2S
Mol. Mass.:
291.369
SMILES:
Cc1occc1C(=O)Nc1nnc(s1)C1CCCCC1
Structure:
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