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Target
Sentrin-specific protease 8
Ligand
BDBM76503
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2560±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76503
Synonyms:
3-chloranyl-N-(5-methyl-1,3-thiazol-2-yl)-1-benzothiophene-2-carboxamide | 3-chloro-N-(5-methyl-1,3-thiazol-2-yl)-1-benzothiophene-2-carboxamide | 3-chloro-N-(5-methyl-2-thiazolyl)-1-benzothiophene-2-carboxamide | 3-chloro-N-(5-methylthiazol-2-yl)benzothiophene-2-carboxamide | MLS000334487 | SMR000249245 | cid_2523343
Type:
Small organic molecule
Emp. Form.:
C13H9ClN2OS2
Mol. Mass.:
308.806
SMILES:
Cc1cnc(NC(=O)c2sc3ccccc3c2Cl)s1
Structure:
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