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Target
Sentrin-specific protease 8
Ligand
BDBM50181684
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2860±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM50181684
Synonyms:
5-(2-methyl-3-phenyl-allylidene)-3-(benzenesulfonylamino)-4-oxo-2-thionothiazolidine | CHEMBL381033 | cid_1998838
Type:
Small organic molecule
Emp. Form.:
C19H16N2O3S3
Mol. Mass.:
416.537
SMILES:
CC(C=C1SC(=S)N(NS(=O)(=O)c2ccccc2)C1=O)=Cc1ccccc1 |w:2.1,20.22|
Structure:
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