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Target
Sentrin-specific protease 8
Ligand
BDBM76714
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2650±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76714
Synonyms:
3-(1H-benzimidazol-2-yl)-8-hydroxy-1-benzopyran-2-one | 3-(1H-benzimidazol-2-yl)-8-hydroxy-2H-chromen-2-one | 3-(1H-benzimidazol-2-yl)-8-hydroxy-coumarin | 3-(1H-benzimidazol-2-yl)-8-hydroxychromen-2-one | 3-(1H-benzimidazol-2-yl)-8-oxidanyl-chromen-2-one | MLS001197729 | SMR000559763 | cid_22424060
Type:
Small organic molecule
Emp. Form.:
C16H10N2O3
Mol. Mass.:
278.2622
SMILES:
Oc1cccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc12
Structure:
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