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Target
Sentrin-specific protease 8
Ligand
BDBM58583
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2810±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM58583
Synonyms:
6-(1H-indol-5-yl)-1-methoxy-9-xanthenone | 6-(1H-indol-5-yl)-1-methoxy-xanthen-9-one | 6-(1H-indol-5-yl)-1-methoxy-xanthone | 6-(1H-indol-5-yl)-1-methoxyxanthen-9-one | MLS001249984 | SMR000685950 | cid_24792639
Type:
Small organic molecule
Emp. Form.:
C22H15NO3
Mol. Mass.:
341.3594
SMILES:
COc1cccc2oc3cc(ccc3c(=O)c12)-c1ccc2[nH]ccc2c1
Structure:
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