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Target
Protein RecA
Ligand
BDBM70702
Substrate
n/a
Meas. Tech.
Intein inhibitors as potential Tuberculosis drugs
IC50
12000±n/a nM
Citation
 PubChem, PC Intein inhibitors as potential Tuberculosis drugs PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM70702
Synonyms:
Chloro-acetic acid N'-(2-hydroxy-2,2-diphenyl-acetyl)-N-p-tolyl-hydrazide | MLS000589422 | N'-(2-chloranylethanoyl)-N'-(4-methylphenyl)-2-oxidanyl-2,2-diphenyl-ethanehydrazide | N'-(2-chloro-1-oxoethyl)-2-hydroxy-N'-(4-methylphenyl)-2,2-diphenylacetohydrazide | N'-(2-chloroacetyl)-2-hydroxy-2,2-diphenyl-N'-(p-tolyl)acetohydrazide | N'-(2-chloroacetyl)-2-hydroxy-N'-(4-methylphenyl)-2,2-diphenylacetohydrazide | SMR000212821 | cid_1920377
Type:
Small organic molecule
Emp. Form.:
C23H21ClN2O3
Mol. Mass.:
408.877
SMILES:
Cc1ccc(cc1)N(NC(=O)C(O)(c1ccccc1)c1ccccc1)C(=O)CCl
Structure:
Search PDB for entries with ligand similarity: