Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM77494
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
>85275±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM77494
Synonyms:
6-butoxy-7-methyl-8-pyrrolo[2,3-g][2,1,3]benzoxadiazolecarboxylic acid ethyl ester | 6-butoxy-7-methyl-pyrrolo[2,3-g][2,1,3]benzoxadiazole-8-carboxylic acid ethyl ester | MLS000043184 | SMR000019805 | cid_3237885 | ethyl 6-butoxy-7-methyl-6H-[1,2,5]oxadiazolo[3,4-e]indole-8-carboxylate | ethyl 6-butoxy-7-methyl-pyrrolo[2,3-g][2,1,3]benzoxadiazole-8-carboxylate | ethyl 6-butoxy-7-methylpyrrolo[2,3-g][2,1,3]benzoxadiazole-8-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H19N3O4
Mol. Mass.:
317.3398
SMILES:
CCCCOn1c(C)c(C(=O)OCC)c2c1ccc1nonc21
Structure:
Search PDB for entries with ligand similarity: