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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM50113680
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM50113680
Synonyms:
(R)-2-(6-(3-chlorophenylamino)-9-isopropyl-9H-purin-2-ylamino)butan-1-ol | 2-[6-(3-Chloro-phenylamino)-9-isopropyl-9H-purin-2-ylamino]-butan-1-ol | CHEMBL306783 | cid_16746116
Type:
Small organic molecule
Emp. Form.:
C18H23ClN6O
Mol. Mass.:
374.868
SMILES:
CC[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1 |r|
Structure:
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