Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM59973
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
360±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM59973
Synonyms:
4-[(5Z)-2,4-diketo-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]thiazolidin-3-yl]butyric acid | 4-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-2,4-bis(oxidanylidene)-1,3-thiazolidin-3-yl]butanoic acid | 4-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]butanoic acid | 4-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-3-thiazolidinyl]butanoic acid | 4-{5-[(E)-2-Methyl-3-phenyl-prop-2-en-(Z)-ylidene]-2,4-dioxo-thiazolidin-3-yl}-butyric acid | MLS000580382 | SMR000220582 | cid_2040656
Type:
Small organic molecule
Emp. Form.:
C17H17NO4S
Mol. Mass.:
331.386
SMILES:
C\C(\C=C1/SC(=O)N(CCCC(O)=O)C1=O)=C/c1ccccc1
Structure:
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