Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68171
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
4730±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68171
Synonyms:
1-amyl-N-(1H-benzimidazol-2-yl)-2-hydroxy-4-keto-quinoline-3-carboxamide | 4-Hydroxy-2-oxo-1-pentyl-1,2-dihydro-quinoline-3-carboxylic acid (1H-benzoimidazol-2-yl)-amide | MLS001047329 | N-(1H-benzimidazol-2-yl)-2-hydroxy-4-oxo-1-pentyl-3-quinolinecarboxamide | N-(1H-benzimidazol-2-yl)-2-hydroxy-4-oxo-1-pentylquinoline-3-carboxamide | N-(1H-benzimidazol-2-yl)-2-oxidanyl-4-oxidanylidene-1-pentyl-quinoline-3-carboxamide | SMR000427412 | cid_1935806
Type:
Small organic molecule
Emp. Form.:
C22H22N4O3
Mol. Mass.:
390.4351
SMILES:
CCCCCn1c2ccccc2c(O)c(C(=O)Nc2nc3ccccc3[nH]2)c1=O
Structure:
Search PDB for entries with ligand similarity: