Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM79489
Substrate
n/a
Meas. Tech.
Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50
EC50
>50000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50 PubChem Bioassay (2011)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM79489
Synonyms:
1-(4-chlorobenzyl)-3-methyl-thieno[2,3-c]pyrazole-5-carboxylic acid [2-(ethylcarbamoylamino)-2-keto-1-methyl-ethyl] ester | 1-[(4-chlorophenyl)methyl]-3-methyl-5-thieno[2,3-c]pyrazolecarboxylic acid [1-(ethylcarbamoylamino)-1-oxopropan-2-yl] ester | SR-02000000330 | SR-02000000330-1 | [1-(ethylcarbamoylamino)-1-oxidanylidene-propan-2-yl] 1-[(4-chlorophenyl)methyl]-3-methyl-thieno[2,3-c]pyrazole-5-carboxylate | [1-(ethylcarbamoylamino)-1-oxopropan-2-yl] 1-[(4-chlorophenyl)methyl]-3-methylthieno[2,3-c]pyrazole-5-carboxylate | cid_44640171
Type:
Small organic molecule
Emp. Form.:
C20H21ClN4O4S
Mol. Mass.:
448.923
SMILES:
CCNC(=O)NC(=O)C(C)OC(=O)c1cc2c(C)nn(Cc3ccc(Cl)cc3)c2s1
Structure:
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