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Target
Neurotensin receptor type 1
Ligand
BDBM79519
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
20700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79519
Synonyms:
1-butyl-2-[2-(4-methylpiperidin-1-yl)-2-oxidanylidene-ethyl]sulfanyl-benzimidazole-5-sulfonamide | 1-butyl-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanylbenzimidazole-5-sulfonamide | 1-butyl-2-[[2-(4-methyl-1-piperidinyl)-2-oxoethyl]thio]-5-benzimidazolesulfonamide | 1-butyl-2-[[2-keto-2-(4-methylpiperidino)ethyl]thio]benzimidazole-5-sulfonamide | MLS000054740 | SMR000064890 | cid_2998956
Type:
Small organic molecule
Emp. Form.:
C19H28N4O3S2
Mol. Mass.:
424.581
SMILES:
CCCCn1c(SCC(=O)N2CCC(C)CC2)nc2cc(ccc12)S(N)(=O)=O
Structure:
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