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Target
Neurotensin receptor type 1
Ligand
BDBM79532
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
3800±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79532
Synonyms:
MLS000544091 | N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-methyl-4-nitro-pyrazole-3-carboxamide | N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-1-methyl-4-nitropyrazole-3-carboxamide | N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-4-nitro-1-methyl-1H-pyrazole-3-carboxamide | N-[4-(4-chlorophenyl)-2-thiazolyl]-1-methyl-4-nitro-3-pyrazolecarboxamide | N-[4-(4-chlorophenyl)thiazol-2-yl]-1-methyl-4-nitro-pyrazole-3-carboxamide | SMR000159572 | cid_1224762
Type:
Small organic molecule
Emp. Form.:
C14H10ClN5O3S
Mol. Mass.:
363.779
SMILES:
Cn1cc(c(n1)C(=O)Nc1nc(cs1)-c1ccc(Cl)cc1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: