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Target
Neurotensin receptor type 1
Ligand
BDBM61707
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
12700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM61707
Synonyms:
5-[(5-cyclohexylsulfanylfuran-2-yl)methylidene]-1,3-diazinane-2,4,6-trione | 5-[[5-(cyclohexylthio)-2-furanyl]methylidene]-1,3-diazinane-2,4,6-trione | 5-[[5-(cyclohexylthio)-2-furyl]methylene]barbituric acid | 5-{[5-(cyclohexylthio)-2-furyl]methylene}pyrimidine-2,4,6(1H,3H,5H)-trione | MLS000730984 | SMR000309359 | cid_16195600
Type:
Small organic molecule
Emp. Form.:
C15H16N2O4S
Mol. Mass.:
320.364
SMILES:
O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]/c2ccc(-[#16]-[#6]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)o2)-[#6](=O)-[#7]-1
Structure:
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