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Target
Neurotensin receptor type 1
Ligand
BDBM79582
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
33000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79582
Synonyms:
1-(4-bromophenyl)-3-(4-morpholinyl)-2-phenyl-1-propanone;hydrochloride | 1-(4-bromophenyl)-3-morpholin-4-yl-2-phenyl-propan-1-one;hydrochloride | 1-(4-bromophenyl)-3-morpholin-4-yl-2-phenylpropan-1-one;hydrochloride | 1-(4-bromophenyl)-3-morpholino-2-phenyl-propan-1-one;hydrochloride | MLS001173629 | SMR000538743 | cid_24747642
Type:
Small organic molecule
Emp. Form.:
C19H20BrNO2
Mol. Mass.:
374.272
SMILES:
Brc1ccc(cc1)C(=O)C(CN1CCOCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: