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Target
Bcl-2-related protein A1
Ligand
BDBM78808
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
5200±360 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM78808
Synonyms:
2-[4-[2-(4-fluorophenyl)sulfanylethyl]pyridin-1-ium-1-yl]-1-phenyl-ethanone;bromide | 2-[4-[2-(4-fluorophenyl)sulfanylethyl]pyridin-1-ium-1-yl]-1-phenylethanone;bromide | 2-[4-[2-[(4-fluorophenyl)thio]ethyl]-1-pyridin-1-iumyl]-1-phenylethanone;bromide | 2-[4-[2-[(4-fluorophenyl)thio]ethyl]pyridin-1-ium-1-yl]-1-phenyl-ethanone;bromide | 4-{2-[(4-fluorophenyl)thio]ethyl}-1-(2-oxo-2-phenylethyl)pyridinium | MLS000722811 | SMR000304807 | cid_2827177
Type:
Small organic molecule
Emp. Form.:
C21H19FNOS
Mol. Mass.:
352.445
SMILES:
Fc1ccc(SCCc2cc[n+](CC(=O)c3ccccc3)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: