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Target
Tropomyosin alpha-1 chain
Ligand
BDBM53515
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71476±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM53515
Synonyms:
2-[4-[hydroxy(methylcarbamoyl)amino]-2-keto-3,5,5-trimethyl-imidazolidin-1-yl]acetic acid methyl ester | 2-[4-[hydroxy(methylcarbamoyl)amino]-3,5,5-trimethyl-2-oxo-1-imidazolidinyl]acetic acid methyl ester | MLS000038306 | SMR000039581 | cid_658537 | methyl 2-[3,5,5-trimethyl-4-[methylcarbamoyl(oxidanyl)amino]-2-oxidanylidene-imidazolidin-1-yl]ethanoate | methyl 2-[4-[hydroxy(methylcarbamoyl)amino]-3,5,5-trimethyl-2-oxoimidazolidin-1-yl]acetate
Type:
Small organic molecule
Emp. Form.:
C11H20N4O5
Mol. Mass.:
288.3003
SMILES:
CNC(=O)N(O)C1N(C)C(=O)N(CC(=O)OC)C1(C)C
Structure:
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