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Target
Tropomyosin alpha-1 chain
Ligand
BDBM79640
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71465±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM79640
Synonyms:
1-(2-furanyl)-2-[2-imino-3-(phenylmethyl)-1-benzimidazolyl]ethanol;hydrochloride | 2-(3-benzyl-2-imino-benzimidazol-1-yl)-1-(2-furyl)ethanol;hydrochloride | 2-(3-benzyl-2-iminobenzimidazol-1-yl)-1-(furan-2-yl)ethanol;hydrochloride | 2-[2-azanylidene-3-(phenylmethyl)benzimidazol-1-yl]-1-(furan-2-yl)ethanol;hydrochloride | CHEMBL1617679 | MLS000039010 | SMR000037064 | cid_6602705
Type:
Small organic molecule
Emp. Form.:
C20H19N3O2
Mol. Mass.:
333.3838
SMILES:
OC(Cn1c2ccccc2n(Cc2ccccc2)c1=N)c1ccco1
Structure:
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