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Target
DNA dC->dU-editing enzyme APOBEC-3A
Ligand
BDBM33085
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen
Temperature
298.15±n/a K
IC50
>100000±n/a nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:
ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23013.77
Organism:
Homo sapiens (Human)
Description:
gi_21955158
Residue:
199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
  
Inhibitor
Name:
BDBM33085
Synonyms:
4-[(4-chloranyl-1,2,3-dithiazol-5-ylidene)amino]benzenecarbonitrile | 4-[(4-chloro-5-dithiazolylidene)amino]benzonitrile | 4-[(4-chlorodithiazol-5-ylidene)amino]benzonitrile | MLS000519626 | SMR000130044 | cid_715698
Type:
Small organic molecule
Emp. Form.:
C9H4ClN3S2
Mol. Mass.:
253.731
SMILES:
Clc1nss\c1=N\c1ccc(cc1)C#N
Structure:
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