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Target
C-C chemokine receptor type 6
Ligand
BDBM33124
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
29300±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM33124
Synonyms:
2-Chloro-3-[4-(2-nitro-phenyl)-piperazin-1-yl]-[1,4]naphthoquinone | 2-chloranyl-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione | 2-chloro-3-[4-(2-nitrophenyl)-1-piperazinyl]naphthalene-1,4-dione | 2-chloro-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione | 2-chloro-3-[4-(2-nitrophenyl)piperazino]-1,4-naphthoquinone | MLS000588199 | SMR000220218 | cid_4561725
Type:
Small organic molecule
Emp. Form.:
C20H16ClN3O4
Mol. Mass.:
397.812
SMILES:
[O-][N+](=O)c1ccccc1N1CCN(CC1)C1=C(Cl)C(=O)c2ccccc2C1=O |c:17|
Structure:
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