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Target
C-C chemokine receptor type 6
Ligand
BDBM66034
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
21600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM66034
Synonyms:
(6E)-4-methyl-6-(1,3-thiazol-2-ylhydrazinylidene)cyclohexa-2,4-dien-1-one | (6E)-4-methyl-6-(2-thiazolylhydrazinylidene)-1-cyclohexa-2,4-dienone | (6E)-4-methyl-6-(thiazol-2-ylhydrazono)cyclohexa-2,4-dien-1-one | MLS001360007 | SMR001224337 | cid_9576957
Type:
Small organic molecule
Emp. Form.:
C10H9N3OS
Mol. Mass.:
219.263
SMILES:
Cc1ccc(O)c(c1)N=Nc1nccs1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: