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Target
Tropomyosin alpha-1 chain
Ligand
BDBM80747
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
IC50
3888±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM80747
Synonyms:
4-oxidanyl-6-phenylazanyl-naphthalene-1-sulfonic acid | 6-anilino-4-hydroxy-1-naphthalenesulfonic acid | 6-anilino-4-hydroxy-naphthalene-1-sulfonic acid | 6-anilino-4-hydroxynaphthalene-1-sulfonic acid | MLS002637586 | SMR001547116 | cid_219926
Type:
Small organic molecule
Emp. Form.:
C16H13NO4S
Mol. Mass.:
315.344
SMILES:
Oc1ccc(c2ccc(Nc3ccccc3)cc12)S(O)(=O)=O
Structure:
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