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Target
Cysteine protease ATG4B
Ligand
BDBM48845
Substrate
n/a
Meas. Tech.
Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B.
IC50
4470±n/a nM
Citation
 PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay (2011)[AID] 
Target
Name:
Cysteine protease ATG4B
Synonyms:
APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44279.79
Organism:
Homo sapiens (Human)
Description:
gi_47132611
Residue:
393
Sequence:
MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
  
Inhibitor
Name:
BDBM48845
Synonyms:
1-cetyl-3-methyl-imidazol-3-ium;bromide | 1-hexadecyl-3-methyl-imidazol-3-ium;bromide | 1-hexadecyl-3-methylimidazol-3-ium;bromide | 3-hexadecyl-1-methyl-1H-imidazol-3-ium | MLS000720114 | SMR000304643 | cid_2846928
Type:
Small organic molecule
Emp. Form.:
C20H39N2
Mol. Mass.:
307.5365
SMILES:
CCCCCCCCCCCCCCCCn1cc[n+](C)c1
Structure:
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